Featured News

Response and remission rates were the same in the drug versus placebo groups, and Lexapro increased suicidality sixfold.

Antidepressant users share their frustrations towards a healthcare system that overprescribes but is ill-equipped to support with discontinuation and withdrawal symptoms.

In a study of people with borderline personality disorder, only ADHD stimulants were associated with a decrease in suicide.

Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Post-SSRI sexual dysfunction (PSSD) may be a common adverse effect of antidepressants. Researchers are now attempting to understand the neurobiology behind it.

Researchers find that adverse effects often last over a year, with many users experiencing substantial life changes.

A new study published in JAMA Psychiatry connects antipsychotics with damage to the brain in multiple areas.

New research by Jim van Os and Peter Groot finds that using hyperbolic tapering to discontinue antidepressants reduces withdrawal effects.

People with "serious mental illness" who stop taking antipsychotics are more likely to recover, even when accounting for baseline severity.

Males taking antidepressants were at 100 times the risk of erectile dysfunction compared with the healthy population and more than three times the risk even after controlling for other variables.

Moncrieff et al. respond to the contradictory and, in some cases, false concerns raised by these critics of their serotonin review.

Robin Williams had "therapeutic" levels of the tetra-cyclic antidepressant mirtazapine in his blood at the time of his suicide, according to the coroner's report...

Risk of depression increased when children were taking methylphenidate for ADHD, but once they stopped taking the drug, depression risk dropped to normal levels.

Leading ADHD researchers outline four mistakes that turned ADHD from a description of behavior into a medical disease.

In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

The antipsychotic clozapine, considered the “gold-standard” treatment for psychosis, was found to increase the risk of blood and lymph system cancers.

A new study finds that newborn babies experience antidepressant withdrawal after birth if their mothers take SSRIs when pregnant.

Combining drugs and therapy also did not lead to better depression outcomes than therapy alone.

A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

Amid growing mental health crisis, research raises questions about the mass rollout of brief psychotherapies in Australia.

New study finds polypharmacy for 73% of older adults on antidepressants, with 56% at risk of harmful drug interactions.

A new Cochrane review details the lack of evidence for antidepressants in the treatment of chronic pain.

World Psychiatry article challenges conventional antidepressant prescription practices.

Genetic testing may help reduce the length of time people experience the harmful effects of antidepressant drugs, but it is not helpful for predicting efficacy.