Antidepressants

New study confirms previous evidence that antidepressant use is linked to developing type 2 diabetes.

A systematic review of literature and meta-analysis indicates that there is no clinically or statistically significant effect of antidepressant dose increase after nonresponse to initial treatment.

Researchers review a new synthesis of the existing evidence and conclude that the harms of antidepressants outweigh any benefits.

New study finds that Medicaid enrolled youth were 14 times more likely to be on an antidepressant in 2014 than in 1987.

MiA blogger Jeffrey Lacasse's study of psychiatric prescribing in response to perinatal/neonatal death (co-authored with Joanne Cacciatore) finds that 37% of participants in an...

Researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening.

Research in Translational Psychiatry finds that childhood maltreatment and trauma predict a greater likelihood of developing chronic depression, and a reduced likelihood of responding to treatment...

Despite their finding, the researchers suggest that SSRIs be given to people who do not meet criteria for depression or anxiety.

More than ten-percent of adults in the United States are currently prescribed at least one psychiatric medication but there is currently a lack of research on the prevalence of adverse drug events (ADEs) associated with these prescriptions outside of clinical trials.

Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.

A new study finds that anticholinergic drugs, like antidepressants and antipsychotics, are associated with mild cognitive decline.

A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.

Use of antidepressants increased the risk of organ-specific malformations in women with depression

A trial of a new process of identifying drugs that can disrupt sex hormones singled out Paxil from 446 common drugs as having a weak...

Pregnant women taking antidepressant medications, especially during the second trimester, have an increased risk of preeclampsia, a potentially serious or even fatal condition.

A new study, published in Psychological Medicine, found evidence for a specific type of publication bias distorting the evidence about antidepressant efficacy.

A randomized, controlled study by the Department of Pharmacology of Government Medical College in Bhavnagar, Gujarat, India found that in a study of 60...

Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

A new study found that taking antidepressants did not improve quality of life.

A study published in this month’s issue of the Journal of Clinical Psychiatry found that the use of antidepressant drugs was associated with an...

The BMJ’s clinical editor takes issue with uncritical media coverage of antidepressant network meta-analysis, outlining reporting missteps.

A new review, published in BMJ Evidence-Based Medicine, concludes that antidepressants should not be used as the risks outweigh evidence for benefits.

STAT recently published an opinion piece arguing that the black box warning on antidepressants has led to an increase in adolescent suicide. It is easily debunked, and reveals once again how our society is regularly misled about research findings related to psychiatric drugs. STAT has lent its good name to a false story that, unfortunately, will resonate loudly with the public.

After 15 years, the founder of SurvivingAntidepressants.org, Adele Framer, shares what she has learned about the science of withdrawing from psychiatric drugs.

That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.