Antidepressant Use Associated With Menstruation Disorders

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In a study of 793 women taking antidepressants and 639 not taking them, researchers in Turkey found that menstruation disorders were significantly associated with...

Prescription Drugs May Cause One Third of All Birth Defects

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Up to a third of all birth defects may be linked to prescription drugs, according to a review of the evidence published in The...

SSRIs: More Harm Than Good

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Beginning with an "evolutionary analysis" and a review of serotonin's role in the body, researchers from Canada and the U.S. conduct a thorough review...

Publication Bias in Literature on Antidepressants for Autism

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Researchers at the University of Michigan reviewed published and unpublished trials of serotonin receptor inhibitors (SRI) for the treatment of autism spectrum disorders (ASD)....

Minimal Empirical Support for Antidepressant Treatment in Young People

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Researchers from Australia reviewed the existing literature for good-quality evidence of effective prevention and treatment of depression in young people. Prevention research was dominated...

SSRIs Significantly Increase Falls in Dementia, Even at Low Doses

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Researchers in the Netherlands followed 248 nursing home residents with dementia for two years, finding that even 25% of the defined daily dose of...

Benzodiazepine & SSRI Addiction and Withdrawal

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The May issue of Addiction includes a review of pharmacological and phenomenological issues around benzodiazepine (BZD) and SSRI discontinuation.  Definitions, perceptions and management of the...

Study of Antidepressants and Suicide is Retracted

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A controversial 2010 paper, "Antidepressant Medication Prevents Suicide in Depression", has been retracted by Acta Psychiatrica Scandinavica. In a contemporaneous issue of British Journal of...

Antidepressants and Advertising: Psychopharmaceuticals in Crisis

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An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how "drug marketing portrays...

Antidepressants, Not Depression, Raise Risk of Preeclampsia in Pregnancy

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In a study of 69,448 pregnant women with depression, researchers from the Harvard school of public health found that use of SSRI (selective serotonin...

Hypertension in Pregnancy 50% More Likely With SSRIs

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Researchers in Montreal found in a sample of 1,216 pregnant women that those who used antidepressants were at least 50% more likely to experience...

Living Alone Nearly Doubles Antidepressant Use

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Finnish researchers found that in a study of 3471 men and women, those living alone were almost twice as likely to use an antidepressant....

Women on SSRIs Less Likely To Breastfeed

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In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

Brain Volume Recovers With Remission, Not With Medication

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In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...

SSRIs Cause Delayed Head Growth and Premature Birth

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In a study of 7,696 pregnant women, researchers in the Netherlands and the U.S. found that SSRIs caused slower head growth and premature birth....

Antidepressant Use Associated with Brain Atrophy and Lesions in Elderly

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In a study of 630 elderly Manhattanites without dementia, researchers from the Netherlands found that antidepressant use was associated with significantly more brain atrophy,...

Antidepressant Use and Cognitive Impairment After Menopause

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A study of 6,998 postmenopausal women followed over 7.5 years found that antidepressant use correlated with a 70% increased risk of cognitive impairment. The...

Cumulative Risk of Impairment and Death From Anticholinergic Medication

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The New York Times reports that a two-year longitudinal study of over 13,000 men and women over 65 found that anticholinergic medications, which include many...

Antidepressants Have No Effect On Bipolar Depression

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In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...

Suicidal Thoughts and Behavior With Antidepressant Treatment: A Reanalysis

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In 2004 and 2006, the FDA concluded that SSRI antidepressants increased the risk of suicidal ideation in children and adolescents. However, in this month's...

Antidepressants Increase Suicide Risk in Children and Adolescents

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In a meta-analysis of studies of 6039 individuals, researchers in the UK determined that, consistent with previous meta-analysses, antidepressants increased "suicide-related outcomes."  Read more    ...

Discontinuing Psychotropics Reduces Falls in Elderly

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Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...