Antidepressants

An analysis of FDA adverse event reports related to esketamine shows the potential for negative effects such as suicidal and self-injurious ideation.

New research finds that antidepressants are not effective for bipolar disorder and can worsen symptoms of mania.

A new study looks at how online communities provide information and support for patients experiencing psychiatric drug withdrawal.

Patient advocates join with researchers and service users to present first-hand experiences of antidepressant withdrawal.

Researchers investigate the claim that the introduction of antidepressant drugs led to decreases in suicide rates internationally.

A new study offers promising results for psilocybin-assisted psychotherapy for depression.

Noted antidepressant researcher, Michael Hengartner, summarizes the latest research on the use of antidepressants in children and adolescents.

That is the truth about withdrawal syndrome: It’s like a 50-50 chance that you’re going to have a problem. If you’re in the unlucky half, you’re gonna be really unlucky.

A new study finds that anticholinergic drugs, like antidepressants and antipsychotics, are associated with mild cognitive decline.

Researchers review a new synthesis of the existing evidence and conclude that the harms of antidepressants outweigh any benefits.

Royal College of Psychiatrists’ former president demands support for patients coming off antidepressants.

Taking an SSRI antidepressant was associated with a 26% increased risk of violent crime conviction.

Studies that compare the effectiveness of different antidepressant drugs are unreliable, according to new research in BMC Psychiatry.

We interview Dr. Stuart Shipko, a psychiatrist and author who has a particular interest in the side effects and withdrawal effects of SSRI antidepressants and the need for informed consent when prescribing.

A new study by Peter Groot and Jim van Os investigated whether tapering strips can help people stop using antidepressants.

A new review of strategies to support both patients and practitioners through the process of discontinuing antidepressants.

National data on rates of youth antidepressant prescription, suicide, and self-harm in Australia sparks public health debate about drug safety.

Study finds an apparent connection between SSRIs, the most commonly prescribed type of antidepressant, and increased risk of violent crime.

Once an appropriate statistical method was used, the study findings were “no longer valid,” according to the editors of JAMA and JAMA Psychiatry.

“This is remarkable for drugs that are used to treat depressive symptoms,” write the researchers.

Researchers suggest that because most antidepressant “success” is due to the placebo effect, they may never find a way to predict outcomes.

Trials of antidepressants for relapse prevention are confounded by withdrawal effects caused by the drugs.

A new study indicates that popular online resources do not accurately present the scientific evidence on the risks and benefits of antidepressants.

New study finds that Medicaid enrolled youth were 14 times more likely to be on an antidepressant in 2014 than in 1987.

Researchers at Johns Hopkins test paroxetine on developing brain cells and discover numerous neurotoxic effects.