Antidepressants

According to patient reports, SSRI antidepressants most frequently lead to the subjective experience of emotional blunting.

A review of clinical practice guidelines for antidepressant discontinuation from across the English-speaking world reveals major pitfalls.

Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.

Antidepressant trials with negative results are still more likely than not to either be misleadingly spun as positive or unpublished.

A study in JAMA Neurology finds that antidepressants do not reduce depression symptoms more than placebo in patients recovering from a stroke.

A review of research on antidepressant efficacy finds that an unfavorable risk-to-benefit ratio.

A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Meta-analysis finds that the placebo run-in methodology reduces the placebo effect and finds antidepressants to be less useful.

Leading researchers point out that a new antidepressant study in NEJM failed to account for withdrawal symptoms, casting doubt on the results.

In this podcast, we hear from the renowned clinician and researcher Dr. Giovanni Fava about his latest book entitled “Discontinuing Antidepressant Medications”.

Researchers developed a rating scale to better assess service users’ experiences tapering antidepressant and/or antipsychotic medication.

A new study finds that newborn babies experience antidepressant withdrawal after birth if their mothers take SSRIs when pregnant.

A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.

A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.

Researchers again debunk the claim that the FDA black box warnings on antidepressants led to more suicides.

“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

The prominent psychiatrist explores why antidepressants remain highly overprescribed and offers solutions to the problem.

While professional guidelines recommend antidepressants for back pain, researchers point out the lack of evidence for their usefulness.

Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research.

After 15 years, the founder of SurvivingAntidepressants.org, Adele Framer, shares what she has learned about the science of withdrawing from psychiatric drugs.

Adverse physiological symptoms of antidepressant withdrawal are regularly mistaken to be other problems to the detriment of the patient.

Bias and financial conflicts in antidepressant trials “contribute to systematic underestimation of risk in the published literature.”

Due to lackluster antidepressant study results, researchers test if subgroups of depressed patients show greater improvement.

Protracted Withdrawal Syndrome characterized by long-term adverse experiences after coming off of antidepressants.